Cancer and Diagnostics

Cancer Immunology and Immunotherapy

The "Cancer Immunology and Immunotherapy" session at the 25th World Congress on Cancer and Diagnostics will explore the dynamic and rapidly evolving field of cancer immunology and the development of innovative immunotherapeutic approaches. This session aims to bring together researchers, clinicians, and industry professionals to discuss the latest advances in harnessing the immune system to fight cancer, understand the underlying immunological mechanisms, and explore new therapeutic strategies.

Key Topics:

1. Fundamentals of Cancer Immunology: This segment will provide an overview of the fundamental principles of cancer immunology, including the interactions between cancer cells and the immune system. Discussions will cover how tumors evade immune surveillance and the role of tumor-associated antigens, immune checkpoints, and the tumor microenvironment in cancer progression.

2. Immunotherapy Strategies: Attendees will learn about the various immunotherapy modalities currently being used or developed, including:

   • Checkpoint Inhibitors: The session will cover immune checkpoint inhibitors such as PD-1, PD-L1, and CTLA-4 blockers, discussing their mechanisms of action, clinical efficacy, and emerging combination strategies.
   • CAR-T Cell Therapy: Presentations will focus on chimeric antigen receptor (CAR) T-cell therapy, highlighting recent advances, challenges in manufacturing, and outcomes in different cancer types.
   • Cancer Vaccines: Discussions will include therapeutic cancer vaccines designed to stimulate the immune system to target specific cancer antigens, as well as prophylactic vaccines for cancer prevention.

3. Overcoming Resistance and Enhancing Efficacy: This topic will address the challenges of resistance to immunotherapy and strategies to overcome these obstacles. Presentations will explore mechanisms of resistance, predictive biomarkers for response, and novel approaches to enhance the efficacy of immunotherapy.

4. Combining Immunotherapy with Other Modalities: The session will examine the integration of immunotherapy with other treatment modalities such as chemotherapy, targeted therapy, and radiation. The aim is to discuss how combination therapies can synergistically improve patient outcomes and address resistance.

5. Personalized and Precision Immunotherapy: Attendees will explore the role of personalized and precision medicine in immunotherapy, including the use of genomic and proteomic profiling to tailor immunotherapeutic approaches to individual patients' profiles.

6. Clinical Trials and Future Directions: The session will feature updates on ongoing clinical trials and emerging research in cancer immunotherapy. Discussions will highlight promising new therapies, trial results, and the future direction of immunotherapy research.