Cancer and Diagnostics

Molecular Biology of Cancer

The "Molecular Biology of Cancer" session at the 25th World Congress on Cancer and Diagnostics is designed to delve into the intricate mechanisms that drive cancer at a molecular level. This session will bring together leading researchers, oncologists, and medical professionals to discuss the latest discoveries and advancements in the field.

Key Topics:

1. Genomic Instability and Mutation: This segment will explore how genetic mutations and chromosomal instability contribute to cancer development. Speakers will present the latest findings on the identification of oncogenes and tumor suppressor genes, highlighting their roles in tumorigenesis.

2. Epigenetics in Cancer: Attendees will learn about the role of epigenetic modifications, such as DNA methylation and histone modification, in cancer progression. The session will cover how these changes can influence gene expression and contribute to the heterogeneity of tumors.

3. Cancer Metabolism: This topic focuses on the altered metabolic pathways in cancer cells. Discussions will include the Warburg effect, metabolic reprogramming, and the potential for targeting cancer metabolism in therapeutic strategies.

4. Signal Transduction Pathways: Presentations will cover key signal transduction pathways, such as the PI3K/AKT, RAS/RAF/MEK/ERK, and WNT/β-catenin pathways, which play critical roles in cell proliferation, survival, and differentiation. Insights into how these pathways are dysregulated in cancer will be provided.

5. Molecular Targets for Cancer Therapy: The session will also address current and emerging molecular targets for cancer therapy, including targeted therapies and immunotherapies. Discussions will emphasize the development of novel drugs and the use of biomarkers for personalized medicine.